Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/295696781?client_source=feed&format=rss
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Sunday, March 31, 2013
Pope makes Easter plea for Mideast peace
VATICAN CITY (AP) ? Pope Francis delivered a plea for peace in his first Easter Sunday message to the world, decrying the seemingly endless conflicts in the Middle East and on the Korean peninsula after celebrating Mass at an outdoor altar before more than 250,000 people in flower-bedecked St. Peter's Square.
Francis shared in his flock's exuberance as they celebrated Christianity's core belief that Jesus Christ rose from the dead following crucifixion. After Mass, he stepped aboard an open-topped white popemobile for a cheerful spin through the joyous crowd, kissing babies and patting children on the head.
One admirer of both the pope and of the pope's favorite soccer team, Argentina's Saints of San Lorenzo, insisted that Francis take a team jersey he was waving at the pontiff. A delighted Francis obliged, briefly holding up the shirt, and the crowd roared in approval.
Francis has repeatedly put concern for the poor and suffering at the center of his messages, and he pursued his promotion of the causes of peace and social justice in the Easter speech he delivered from the central balcony of St. Peter's Basilica, the same vantage point above the square where he was introduced to the world as the first Latin American pope on March 13.
The Roman Catholic leader aimed his Easter greetings at "every house and every family, especially where the suffering is greatest, in hospitals, in prisons." Francis prayed that Jesus would inspire people to "change hatred into love, vengeance into forgiveness, war into peace."
As popes before him have, he urged Israelis and Palestinians to resume peace talks and end a conflict that "has lasted all too long." And, in reflecting on the two-year-old Syrian crisis, Francis asked, "How much suffering must there still be before a political solution" can be found?
The pope also expressed desire for a "spirit of reconciliation" on the Korean peninsula, where North Korea says it has entered "a state of war" with South Korea. He also decried warfare and terrorism in Africa, as well as what he called the 21st century's most extensive form of slavery: human trafficking.
The first pontiff to come from the Jesuits, an order with special concern for the poor, and the first pope to name himself after St. Francis, a medieval figure who renounced wealth to preach to the down-and-out, Francis lamented that the world is "still divided by greed looking for easy gain."
Earlier, wearing cream-colored vestments, Francis celebrated Mass on the esplanade in front of the basilica at an altar set up under a white canopy. He frequently bowed his head as if in silent reflection.
The sun competed with clouds in the sky Sunday, but the square was a riot of floral color in Rome, where chilly winter has postponed the blossoming of many flowers. Yellow forsythia and white lilies shone, along with bursts of lavender and pink, from potted azalea, rhododendron, wisteria and other plants.
Francis thanked florists from the Netherlands for donating the flowers. He also advised people to let love transform their lives, or as he put it, "let those desert places in our hearts bloom."
The Vatican had prepared a list of brief Easter greetings in 65 languages, but Francis didn't read them. The Vatican didn't say why not, but has said that the new pope, at least for now, feels at ease using Italian, the everyday language of the Holy See. Francis also has stressed his role as a pastor to his flock, and, as Bishop of Rome, Italian would be his language.
The pontiff improvised his parting words to the crowd. He repeated his Easter greeting to those "who have come from all over the world to this square at the heart of Christianity" as well as to those "linked by modern technology," a reference to TV and radio coverage as well as social media.
Francis added that he was especially remembering "the weakest and the neediest" and praying that all of humanity be guided along "the paths of justice, love and peace."
In another departure from Easter tradition, Francis won't be heading for some post-holiday relaxation at the Vatican's summer palace in Castel Gandolfo, in the hills southeast of Rome. That retreat is already occupied by his predecessor, Benedict XVI, who went there in the last hours of his papacy on Feb. 28. Benedict became the first pope in 600 years to resign from the position, and eventually is to move back to the Vatican, after a convent there is readied for him.
Francis so far has declined to move into Benedict's former apartment in the Apostolic Palace, into the rooms whose studio overlooks St. Peter's Square. He is still in the Vatican hotel where earlier this month he was staying along with other cardinals participating in the secret conclave to choose Benedict's successor.
While Francis has just begun to make his mark on the church, it is plain he has little desire to embrace much of the pomp customarily associated with the office.
Source: http://news.yahoo.com/pope-makes-easter-pleas-mideast-peace-101523086.html
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Pat Riley to Danny Ainge: Shut up
NEW ORLEANS (AP) ? Miami Heat President Pat Riley has added another chapter to his rivalry with the Boston Celtics.
After LeBron James complained about calls and Boston Celtics president of basketball operations Danny Ainge chided him for it, Riley lashed back Friday night.
Riley's response: "Danny Ainge needs to shut the (expletive) up and manage his own team."
This saga started Wednesday after Miami's 27-game winning streak ended in Chicago. James told reporters that night that he does not believe some of the hard fouls he takes are "basketball plays." A day later, Ainge told Boston radio station WEEI that "it's almost embarrassing that LeBron would complain about officiating."
Riley was clearly irked, calling Ainge "the biggest whiner going when he was a player."
The Heat and Celtics play April 12 in Miami.
Miami beat New Orleans 108-89 on Friday night, with James leading the way with 36 points. When informed afterward of the statement, James said he appreciated Riley having his back.
"That's who we are," James said. "We ride together, all of us, from the top to the bottom. We all protect each other on and off the floor and it was big-time to see that."
Source: http://news.yahoo.com/pat-riley-danny-ainge-shut-010424469--spt.html
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Shroud of Turin authenticity up for debate again after new report (+video)
Scientists at the University of Padua in Italy have used infrared light and spectroscopy (the study of a physical object's interaction with electromagnetic radiation) to examine the shroud and found that it's actually much older than a previous study found.
Williams Jones, Shenadoah, Pa., shows some of the points of interest in the Shroud of Turin replica on display in front of the altar after the Divine Liturgy during the Shroud of Turin exhibit at St. Michael's Ukrainian Catholic Church in Shenandoah, Pa., in Feb.
Jacqueline Dormer/The Republican-Herald/AP
EnlargeThe Shroud of Turin, an icon of faith and controversy among Christians, is back in the news.
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The Shroud of Turin - the cloth that some have claimed was used to wrap the body of Jesus after his crucifixion - is the subject of a new book that claims it is 2,300 years old. Gayle King reports.The linen cloth, allegedly the burial shroud of Jesus, was closely examined in 1988 in laboratories in Switzerland, England and the United States using carbon-14 dating techniques, the?Telegraph?reports.
Those examinations of the shroud ? which bears the image of a man's face and torso ? dated the cloth from 1260 to 1390, supporting claims that it's merely an elaborate medieval hoax, as Jesus' life is thought to have come to an end in A.D. 33.
Some believers, however, insisted that the linen fibers used in the 1988 examinations were not from the original shroud, but rather from a portion of the cloth that had been repaired after suffering fire damage in the Middle Ages.
Now, scientists at the University of Padua in Italy have used infrared light and spectroscopy (the study of a physical object's interaction with electromagnetic radiation) to examine the shroud and found that it's actually much older, the Telegraph reports.?
In his recent book, "Il Mistero della Sindone," translated as "The Mystery of the Shroud," (Rizzoli, 2013), Giulio Fanti, a professor of mechanical engineering at Padua University, said his analysis proves the shroud dates from 280 B.C. to A.D. 220 ? meaning it existed during Jesus' lifetime, the?Guardian?reports. [Religious Mysteries: 8 Alleged Relics of Jesus]
The Shroud of Turin is said to be the cloth that covered Jesus' body after the crucifiction. Previous examinations that dated the shroud to the Middle Ages mesh with historical records, which don't start mentioning the cloth until that time. But some researchers believe the shroud is older. Thomas de Wesselow, author of "The Sign: The Shroud of Turin and the Secret of the Resurrection" (Dutton Adult, 2012), argues that medieval artists did not paint in photorealistic style, and that a forged shroud created in the Middle Ages would be an anachronism.?
That doesn't mean the shroud is evidence of a miracle, however, de Wesselow told LiveScience last year. He believes natural chemical reactions caused by a decomposing body and annoiting oils could have created the body imprint on the shroud, which may have then been?used as evidence of Christ's resurrection.?
For the first time in 30 years, the shroud will be shown on television this Saturday (March 30), the Guardian reports. Before leaving the papacy,?Benedict XVI?approved a special broadcast of the shroud to be held at the Turin Cathedral, where the cloth is preserved in a climate-controlled case.
And for those who want an even more intimate examination of the cloth, a new mobile app, Shroud 2.0, was just released on Good Friday (March 29),?Zenit.org?reports.
Designed in collaboration with the Museum of the Holy Shroud and the Archdiocese of Turin, Shroud 2.0 synthesizes 1,649 high-definition photographs into a single 12-billion-pixel image. An Android version is also being developed, Zenit reports.
Follow Marc Lallanilla on?Twitter?and?Google+. Follow us?@livescience,?Facebook?&?Google+. Original article onLiveScience.com.
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Saturday, March 30, 2013
Understanding Acne Risks | Tips on Food Fitness Life Love
There are several factors that trigger risks of acne. It is important to understand these factors to be able to fight off acne and promote healthy, clear, and glowing skin.
First, it is important to understand that the tendency to develop acne runs in families. Hence, you are more likely to develop the condition if your parents suffered from the same. It has been proved that the risk of developing acne is highest during teenage. Another common period that is popular for acne development is young adult years.
During teenage, hormones such as testosterone are at their peak and keep on increasing. Women at the age of menstruation can also develop acne. Many women are known to have experienced acne flare-ups in the days just before their menstrual periods.
There are certain factors that can make acne worse or irritate the condition more. Some of these include the following listed below:
Skin Abuse
Wearing straps or other tight-fitting items that rub against the skin can promote irritation. Football players who wear shoulder pads may also experience the same problem.
Excess and Constant Rubbing
Using equipment that rubs against the body constantly is harmful. For instance, a violin that is held between the shoulder and cheek can make the condition worse. Other elements such as helmets, headbands, bra straps, turtleneck sweaters may also cause acne to get worse.
Products
Using certain skin and hair care products that contain irritating substances is harmful. This can trigger acne or make it worse.
Washing and Scrubbing
Washing the face too often or scrubbing the face too hard can develop acne.
Touch Me Not
Most people have a habit of touching the face a lot. This tends to irritate the skin or allow germs, dust, and other elements enter the skin pores. This can develop or aggravate acne.
Soap and Water
It is crucial to stay away from harsh soaps that keep disturb the pH balance of skin. Washing face with very hot water can also cause acne to get worse.
Medications
Certain medicines, such as corticosteroids, types of barbiturates, or lithium can cause acne. Those who take anabolic steroids are also at risk for getting acne.
Stress
Research and studies have proved that experiencing a lot of stress can make the condition worse.
Excess Sweating
People who sweat a lot or indulge in activities that make them sweat a lot are at risk of developing acne.
Hair on Face
If you adopt styles such as bangs, fringes or like having hair hanging in the face, the chances of developing acne are bright. This is because hair makes the skin oilier.
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Tags: acne face wash, acne home remedies, acne scars, acne treatment, hand washing, home remedy for acne, home treatment for acne, how to wash hands, natural remedies for acne, remedies for acne, skin acneSource: http://www.foodfitnesslifelove.com/beauty/understanding-acne-risks/
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Friday, March 29, 2013
Biological transistor enables computing within living cells
Mar. 28, 2013 ? When Charles Babbage prototyped the first computing machine in the 19th century, he imagined using mechanical gears and latches to control information. ENIAC, the first modern computer developed in the 1940s, used vacuum tubes and electricity. Today, computers use transistors made from highly engineered semiconducting materials to carry out their logical operations.
And now a team of Stanford University bioengineers has taken computing beyond mechanics and electronics into the living realm of biology. In a paper to be published March 28 in Science, the team details a biological transistor made from genetic material -- DNA and RNA -- in place of gears or electrons. The team calls its biological transistor the "transcriptor."
"Transcriptors are the key component behind amplifying genetic logic -- akin to the transistor and electronics," said Jerome Bonnet, PhD, a postdoctoral scholar in bioengineering and the paper's lead author.
The creation of the transcriptor allows engineers to compute inside living cells to record, for instance, when cells have been exposed to certain external stimuli or environmental factors, or even to turn on and off cell reproduction as needed.
"Biological computers can be used to study and reprogram living systems, monitor environments and improve cellular therapeutics," said Drew Endy, PhD, assistant professor of bioengineering and the paper's senior author.
The biological computer
In electronics, a transistor controls the flow of electrons along a circuit. Similarly, in biologics, a transcriptor controls the flow of a specific protein, RNA polymerase, as it travels along a strand of DNA.
"We have repurposed a group of natural proteins, called integrases, to realize digital control over the flow of RNA polymerase along DNA, which in turn allowed us to engineer amplifying genetic logic," said Endy.
Using transcriptors, the team has created what are known in electrical engineering as logic gates that can derive true-false answers to virtually any biochemical question that might be posed within a cell.
They refer to their transcriptor-based logic gates as "Boolean Integrase Logic," or "BIL gates" for short.
Transcriptor-based gates alone do not constitute a computer, but they are the third and final component of a biological computer that could operate within individual living cells.
Despite their outward differences, all modern computers, from ENIAC to Apple, share three basic functions: storing, transmitting and performing logical operations on information.
Last year, Endy and his team made news in delivering the other two core components of a fully functional genetic computer. The first was a type of rewritable digital data storage within DNA. They also developed a mechanism for transmitting genetic information from cell to cell, a sort of biological Internet.
It all adds up to creating a computer inside a living cell.
Boole's gold
Digital logic is often referred to as "Boolean logic," after George Boole, the mathematician who proposed the system in 1854. Today, Boolean logic typically takes the form of 1s and 0s within a computer. Answer true, gate open; answer false, gate closed. Open. Closed. On. Off. 1. 0. It's that basic. But it turns out that with just these simple tools and ways of thinking you can accomplish quite a lot.
"AND" and "OR" are just two of the most basic Boolean logic gates. An "AND" gate, for instance, is "true" when both of its inputs are true -- when "a" and "b" are true. An "OR" gate, on the other hand, is true when either or both of its inputs are true.
In a biological setting, the possibilities for logic are as limitless as in electronics, Bonnet explained. "You could test whether a given cell had been exposed to any number of external stimuli -- the presence of glucose and caffeine, for instance. BIL gates would allow you to make that determination and to store that information so you could easily identify those which had been exposed and which had not," he said.
By the same token, you could tell the cell to start or stop reproducing if certain factors were present. And, by coupling BIL gates with the team's biological Internet, it is possible to communicate genetic information from cell to cell to orchestrate the behavior of a group of cells.
"The potential applications are limited only by the imagination of the researcher," said co-author Monica Ortiz, a PhD candidate in bioengineering who demonstrated autonomous cell-to-cell communication of DNA encoding various BIL gates.
Building a transcriptor
To create transcriptors and logic gates, the team used carefully calibrated combinations of enzymes -- the integrases mentioned earlier -- that control the flow of RNA polymerase along strands of DNA. If this were electronics, DNA is the wire and RNA polymerase is the electron.
"The choice of enzymes is important," Bonnet said. "We have been careful to select enzymes that function in bacteria, fungi, plants and animals, so that bio-computers can be engineered within a variety of organisms."
On the technical side, the transcriptor achieves a key similarity between the biological transistor and its semiconducting cousin: signal amplification.
With transcriptors, a very small change in the expression of an integrase can create a very large change in the expression of any two other genes.
To understand the importance of amplification, consider that the transistor was first conceived as a way to replace expensive, inefficient and unreliable vacuum tubes in the amplification of telephone signals for transcontinental phone calls. Electrical signals traveling along wires get weaker the farther they travel, but if you put an amplifier every so often along the way, you can relay the signal across a great distance. The same would hold in biological systems as signals get transmitted among a group of cells.
"It is a concept similar to transistor radios," said Pakpoom Subsoontorn, a PhD candidate in bioengineering and co-author of the study who developed theoretical models to predict the behavior of BIL gates. "Relatively weak radio waves traveling through the air can get amplified into sound."
Public-domain biotechnology
To bring the age of the biological computer to a much speedier reality, Endy and his team have contributed all of BIL gates to the public domain so that others can immediately harness and improve upon the tools.
"Most of biotechnology has not yet been imagined, let alone made true. By freely sharing important basic tools everyone can work better together," Bonnet said.
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The above story is reprinted from materials provided by Stanford University Medical Center.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.
Journal Reference:
- Jerome Bonnet, Peter Yin, Monica E. Ortiz, Pakpoom Subsoontorn, and Drew Endy. Amplifying Genetic Logic Gates. Science, 28 March 2013 DOI: 10.1126/science.1232758
Note: If no author is given, the source is cited instead.
Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.
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Mercedes-Benz introduces B-Class Electric Drive, we go eyes-on
Electric Vehicle choices keep getting more compelling, and Mercedes-Benz is doing its part by unveiling the upcoming B-Class Electric Drive. The B-Class is among the smaller of MB's cars (one step up from the A-Class), fitting squarely in the MPV category. It's basically a mini-minivan. MPVs are small but big enough to be practical, and they tend to be economical. The fully electric powertrain in this 2014 model that just rolled onto the stage here at the New York International Auto Show should go a long way in that regard. Follow us after the break for more details and some photos.
Filed under: Transportation
Source: http://www.engadget.com/2013/03/27/mercedes-benz-b-class-electric-drive/
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Thursday, March 28, 2013
PFT: Did RGIII take veiled shot at Shanahan?
APApparently, Jaguars running back Maurice Jones-Drew wasn?t the only one angry about the anonymous rip jobs on quarterback Blaine Gabbert this offseason.
And Gabbert is willing to admit, to the team?s official website, that he took it personally.
After he was referred to as ?Blame Gabbert,? by anonymous teammates, and an anonymous former coach said ?Nothing?s ever his fault,? Gabbert fired back.
?It pissed me off quite a bit, just because you learn to trust your coaches because you spend so much time with them,? Gabbert said. ?That?s starting now. April 2 through whenever your last game is, you?re with them countless hours every day, six or seven days a week. You learn to value their opinion, trust it. It?s a close-knit grip.
?When you have an anonymous source saying something that couldn?t be further from the truth, it pisses me off. Like I always said, ?Put your name on it.? If you?re going to say something to the media, say it to me. Say who said it. No need to hide behind a computer screen or an anonymous source name when you?re trying to make a point.?
That?s all well and good, and noble, but not the reality of how the NFL works. For one thing, if Gabbert had played to the level he was drafted, he wouldn?t have had as many former coaches saying ugly things about him to choose from.
But Gabbert denied it was motivation.
?When it?s not the truth, it doesn?t really motivate me, although you do have external motivators,? Gabbert said. ?You want to prove every person wrong who says you can?t do your job at a high level. We?re just competitive guys. That?s what makes this job fun.?
The competition begins soon for Gabbert, as they?ll find someone (or two) to go with him and Chad Henne soon.
?The third year is an important year for any quarterback,? Gabbert said. ?It?s where you make the jump. You start playing at a high level. There are still going to be ups and downs. Some guys have off seasons and they?ve been playing 10 years in the NFL. You have to eliminate the peaks and valleys. You have to play at a high level consistently. That?s what I?m looking forward to doing.?
And that?s what the Jaguars are looking for, from Gabbert or someone else.
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Evernote for Windows Phone gets refined UI, document search and more in 3.0 update
Evernote's getting a version 3.0 overhaul for Windows Phone that updates the app with some majorly welcome improvements. Now, users that launch the note-taking app will be greeted by two UI refreshes: a simplified homescreen that gathers all your necessary tools for quick access at a glance and a more compact tag list that's easier to navigate and displays more results. The Evernote team's also added the ability to create checkboxes, group notebooks by "stacks" and pin live-tile shortcuts by long-pressing on tags, notes or notebooks; shortcuts that can be synced across various platforms (i.e., Mac, Windows Phone and Android). And for die-hard organizational freaks that pay for the premium product, the app now features document search -- useful for parsing attached MSWord, OpenOffice or iWork docs. The update's live right now, so it should hit your WP device soon. Or if you're one of the uninitiated, now's a good time to make the jump and connect your life with the cloud.
Filed under: Cellphones, Software, Mobile
Source: Evernote
Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/CVKvEacs-ZM/
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Retiring RIM founder has no plans to sell stake
TORONTO (AP) ? Research In Motion co-founder Mike Lazaridis say he has no plans to sell his significant interest in the BlackBerry maker now that he's retiring as vice chairman and director.
Lazaridis said in an interview with The Associated Press on Thursday that having fulfilled a commitment to the board, he has decided to retire after 29 years with the company.
He says he is leaving RIM in good hands. According to FactSet, Lazaridis is the second biggest shareholder with a 5.7 percent stake.
He and Jim Balsillie had stepped down as co-CEOs in January 2012 after several quarters of disappointing results. Thorsten Heins, the chief operating officer, took over and spent the past year cutting costs and steering Research In Motion Ltd. toward the launch of new BlackBerry 10 phones.
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Wednesday, March 27, 2013
Study finds molecular 'signature' for rapidly increasing form of esophageal cancer
Study finds molecular 'signature' for rapidly increasing form of esophageal cancer
Monday, March 25, 2013During the past 30 years, the number of patients with cancers that originate near the junction of the esophagus and stomach has increased approximately 600 percent in the United States. The first extensive probe of the DNA of these esophageal adenocarcinomas (EACs) has revealed that many share a distinctive mix-up of letters of the genetic code, and found more than 20 mutated genes that had not previously been linked to the disease. The research, led by scientists at Dana-Farber Cancer Institute, the Broad Institute, and other research centers, may offer clues to why EAC rates have risen so sharply. The findings, which are being released as an advanced online publication by Nature Genetics, point to an array of abnormal genes and proteins that may be lynchpins of EAC cell growth and therefore serve as targets for new therapies, according to the study's authors.
"Adenocarcinomas of the esophagus, particularly those that arise at the gastroesophageal junction, were extremely uncommon 40 years ago and now account for approximately 15,000 new cases in the United States each year," said Adam Bass, MD, of Dana-Farber and the Broad Institute, who is co-senior author of the paper with Gad Getz, PhD, of the Broad Institute and Massachusetts General Hospital. "Unfortunately, it's also a disease with a generally poor prognosis: five years after diagnosis, only about 15 percent of patients are still alive. Bass added that despite the increased incidence of EAC, there have been few new approaches to treatment. "The goal of our study was to identify abnormalities within the genome of EAC cells to develop a foundation to better understand these tumors, diagnose them earlier, and develop better treatments," explained Bass.
EAC is thought to be associated with chronic gastroesophageal reflux, which sends stomach acid gurgling into the esophagus. This produces a condition known as Barrett's esophagus, in which cells at the lower end of the esophagus change to resemble cells in the intestine. Patients with Barrett's esophagus often go on to develop EAC.
Researchers don't know why EAC rates are increasing, but they speculate that it may be due to a rise in obesity, particularly in men: A heavier abdomen puts increased pressure on the stomach, causing acid to back up into the esophagus.
In the new study, researchers "sequenced" specific sections of DNA in cells from 149 EAC tissue samples, reading the individual letters of the genetic code within those areas. They focused on the one percent of the genome that holds the codes for making cell proteins. They also sequenced the entire genome ? all the DNA within the cell nucleus ? of cells from 15 of these EAC samples. Prior to this study, the largest sequencing study of EAC involved only a dozen tumor samples.
"We discovered a pattern of DNA changes that had not been seen before in any other cancer type," Getz remarked. The pattern involved a subtle swap in one of the four "nucleobases" that form the rungs of the DNA double helix, often designated by the letters C, T, G, and A. The investigators found that in many places where an A nucleobase was followed by another A nucleobase, the second "A" was replaced by a "C," a process known as transversion.
"We found this type of transversion throughout the genomes of the EAC cells we analyzed," Bass stated. "Overall, about one-third of all the mutations we discovered within these cells involved this type of transversion. In some tumor samples, these transversions accounted for nearly half of all mutations," Getz added.
Although A-to-C changes are not commonly observed in cancer, there is some evidence that oxidative damage can produce these changes. (Oxidative damage occurs when cells cannot neutralize the potentially harmful products of oxygen's reactions with other molecules.) "Gastric reflux can produce this type of damage, suggesting that reflux may underlie this pattern of mutations," Bass commented.
In addition to the mutational "signature" of AA becoming AC, the research team identified 26 genes that were frequently mutated in the tumor samples.
Five of these were "classic cancer genes" that had previously been implicated in EAC, Bass said, and the others were involved in a variety of cell processes.
Among the genes not previously linked to EAC were ELMO1 and DOCK2, mutations that can switch on a gene called RAC1, which can cause cancer cells to invade surrounding tissue. "The discovery of mutated ELMO1 and DOCK2 in many of these tumors may indicate that this invasive process is particularly active in EAC, promoting metastasis," Bass related. "We know that EAC tumors tend to spread at an earlier stage than many other cancers, which may help explain why survival rates for EAC patients tend to be low."
The RAC1 pathway ? the network of genes that control RAC1 activity ? is being pursued for pharmaceutical development. The discovery of ELMO1 and DOCK2 mutations in EAC samples may spur testing of new agents targeting this pathway in EAC, said Bass.
"Identifying the mutated genes within these tumors will help us understand the underlying biology of the disease," said Bass. "It also presents us with a slate of known genetic abnormalities that can someday be used to diagnose the disease at an early stage, classify tumors by the particular mutations within EAC cells, and ultimately develop treatment geared to precisely those mutations."
###
Dana-Farber Cancer Institute: http://www.dfci.harvard.edu
Thanks to Dana-Farber Cancer Institute for this article.
This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.
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AP Source: CBS buys half of TV Guide net for $100M
LOS ANGELES (AP) ? A person familiar with CBS' deal for TV Guide says the broadcaster is buying a 50 percent stake in TV Guide's cable channel and website for nearly $100 million.
The price is less than what JPMorgan Chase's One Equity Partners paid for a similar stake four years ago and brings CBS Corp. into an equal partnership with Lions Gate Entertainment Corp.
The deal terms come from a person who wasn't authorized to speak publicly and spoke on condition of anonymity.
CBS says the channel, available in more than 80 million homes, will continue to focus on entertainment. Details about rebranding it will come. It will combine CBS' programming, production and marketing with Lions Gate's resources in movies, TV shows and digital content.
TV Guide magazine isn't part of the deal.
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ItsTheReal 'Really Rapping' On Upcoming April Fool's Mixtape
'It's taking what you know, like these notorious hip-hop themes, and twisting them a little,' Eric Rosenthal tells MTV News of Urbane Outfitters.
By Rob Markman
ItsTheReal's Jeff and Eric
Photo: MTV News
Source: http://www.mtv.com/news/articles/1704363/its-the-real-jeff-eric-urbane-outfitters-mixtape.jhtml
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Tuesday, March 26, 2013
Laser empties atoms from the inside out
Mar. 25, 2013 ? An international team of plasma physicists has used one of the world's most powerful lasers to create highly unusual plasma composed of hollow atoms.
The experimental work led by scientists from the University of York, UK and the Joint Institute for High Temperatures of Russian Academy of Sciences demonstrated that it is possible to remove the two most deeply bound electrons from atoms, emptying the inner most quantum shell and leading to a distinctive plasma state.
The experiment was carried out using the petawatt laser at the Central Laser Facility at the Science and Technology Facilities Council (STFC) Rutherford Appleton Laboratory to further understanding of fusion energy generation, which employs plasmas that are hotter than the core of the Sun.
The results are reported in the journal Physical Review Letters.
A hollow atom occurs when an electron buried in an atom is removed, usually by being hit by another electron, creating a hole while leaving all the other electrons attached. This process creates plasma, a form of ionised gas. An X-ray is released when the hole is filled.
Normally the process involves removing electrons from the outer shells of atoms first and working inwards. The team of scientists demonstrated a new mechanism for creating hollow atoms that involved emptying atoms from the inside out.
The experimental work used an intense laser, which at one petawatt delivers approximately 10,000 times the entire UK national grid, delivered in a thousand-billionth of a second, onto an area smaller than the end of a human hair.
Dr Nigel Woolsey, from the York Plasma Institute, Department of Physics, at the University of York was the Principal Investigator for the experimental work.
Dr Woolsey said: "At such extraordinary intensities electrons move at close to the speed of light and as they move they create perhaps the most intense X-rays ever observed on Earth. These X-rays empty the atoms from the inside out; a most extraordinary observation and one that suggests the physics of these interactions is likely to change, as lasers become more powerful."
Analysis and theoretical work was led by the Los Alamos National Laboratory, USA and Osaka University, Japan.
The analysis showed the mechanism for hollow atom generation was not due to the collision of electrons or driven by the laser photons, but was driven by the resulting radiation field from the interaction.
Lead author Dr James Colgan, from the Los Alamos National Laboratory, said: "The conditions under which the hollow atoms were produced were highly non-equilibrium and the production mechanism was quite surprising. These results indicate that a little-explored region of physics is now starting to become accessible with the unprecedented intensities reached by the world's leading laser facilities."
Co-author Dr Alexei Zhidkov, from Osaka University, said: "This experiment has demonstrated a situation where X-ray radiation dominates the atomic physics in a laser-plasma interaction; this indicates the importance of X-ray radiation generation in our physics description. Future experiments are likely to show yet more dramatic effects which will have substantial implications for diverse fields such as laboratory-based astrophysics."
If the scientific and technological challenges can be overcome, fusion offers the potential for an effectively limitless supply of safe, environmentally friendly energy. The experimental work was designed to further scientists understanding of how intense lasers can create electron beams with speeds close to the speed of light, then use these beams to heat fusion fuel to thermonuclear temperatures.
Co-author Dr Sergey Pikuz, from the Joint Institute for High Temperatures RAS, said: "The measurements, simulations, and developing physics picture are consistent with a scenario in which high-intensity laser technology can be used to generate extremely intense X-ray fields. This demonstrates the potential to study properties of matter under the impact of intense X-ray radiation."
Co-author Rachel Dance, a University of York PhD physics student, said: "This was a very dynamic experiment which led to an unexpected outcome and new physics. The hollow atom diagnostic was set to measure the hot electron beam current generated by the laser, and the results that came out of this in the end, showed us that the mechanism for hollow atom generation, was not collisional or driven by the laser photons, but by the resulting radiation field from the interaction."
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The above story is reprinted from materials provided by University of York.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.
Journal Reference:
- J. Colgan, J. Abdallah, A. Ya. Faenov, S. A. Pikuz, E. Wagenaars, N. Booth, O. Culfa, R. J. Dance, R. G. Evans, R. J. Gray, T. Kaempfer, K. L. Lancaster, P. McKenna, A. L. Rossall, I. Yu. Skobelev, K. S. Schulze, I. Uschmann, A. G. Zhidkov, N. C. Woolsey. Exotic Dense-Matter States Pumped by a Relativistic Laser Plasma in the Radiation-Dominated Regime. Physical Review Letters, 2013; 110 (12) DOI: 10.1103/PhysRevLett.110.125001
Note: If no author is given, the source is cited instead.
Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.
Source: http://feeds.sciencedaily.com/~r/sciencedaily/matter_energy/physics/~3/aIbLFRa7YGQ/130325093528.htm
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Monday, March 25, 2013
Space probes set to smash into asteroid in 2022
ESA
The ambitious European-led Asteroid Impact and Deflection Assessment mission, or AIDA, is to launch in 2019.
By Miriam Kramer
Space.com
THE WOODLANDS, Texas ? Scientists in Europe and the United States are moving forward with plans to intentionally smash a spacecraft into a huge nearby asteroid in 2022 to see inside the space rock.
The ambitious European-led Asteroid Impact and Deflection Assessment mission, or AIDA, is slated to launch in 2019 to send two spacecraft ? one built by scientists in the U.S, and the other by the European Space Agency ? on a three-year voyage to the asteroid Didymos and its companion. Didymos has no chance of impacting the Earth, which makes it a great target for this kind of mission, scientists involved in the mission said in a presentation Tuesday?here at the 44th annual Lunar and Planetary Science Conference.
Didymos is actually a binary asteroid system consisting of two separate space rocks bound together by gravity. The main asteroid is enormous, measuring 2,625 feet (800 meters) across. It is orbited by a smaller asteroid ?about 490 feet (150 m).
The Didymos asteroid setup is an intriguing target for the AIDA mission because it will give scientists their first close look at a binary space rock system while also yielding new insights into ways to deflect dangerous asteroids that could pose an impact threat to the Earth. [Photos of Potentially Dangerous Asteroids]
"Binary systems are quite common," said Andy Rivkin, a scientist at Johns Hopkins'Applied Physics Laboratory in Laurel, Md., working on the U.S. portion of AIDA project. "This will be our first rendezvous with a binary system."
In 2022, the Didymos asteroids will be about 6.8 million miles (11 million km) from the Earth, during a close approach, which is why AIDA scientists have timed their mission for that year.
Rivkin and his colleagues at Johns Hopkins' Applied Physics Laboratory are building DART (short for Double Asteroid Redirection Test), one of the two spacecraft making up the tag team AIDA mission. Like its acronym suggests, the DART probe will crash directly into the smaller Didymos asteroid while traveling at 14,000 mph (22,530 km/h), creating a crater during an impact that will hopefully sending the space rock slightly off course, Rivkin said.
The European Space Agency is building the second AIDA spacecraft, which is called the Asteroid Impact Monitor (or AIM). AIM will observe the impact from a safe distance, and the probe'sdata will be used with other data collected by telescopes on Earth to understand exactly what the impact did to the asteroid.
"AIM is the usual shoebox satellite," ESA researcher Jens Biele, ?who works on the AIM spacecraft, said. "It's nothing very fancy."
AIDA scientists hope their mission will push the smaller Didymos asteroid off course by only a few millimeters. The small space rock orbits the larger, primary Didymos asteroid once every 12 hours.
The goal, Rivkin said, is to use the DART impact as a testbed for the most basic method of asteroid deflection: a direct collision with a spacecraft. ?If the mission is successful, it could have implications for how space agencies around the world learn how to deflect larger, more threatening asteroid that could pose a threat to Earth, he added.
At the moment, AIDA researchers are not sure of the exact composition of the Didymos asteroids. They could just be a loose conglomeration of rocks traveling together through the solar system, or made of much denser stuff.
But once DART impacts the asteroid, scientists will be able to measure how much the asteroid's orbit is affected as well as classify its surface composition, Rivkin said. And by studying how debris floats outward from the impact site after the crash, researchers could also better prepare for the conditions astronauts may encounter during future manned missions to asteroids ? such as NASA's project to send astronauts to an asteroid by 2025, he added.
The AIDA mission's AIM spacecraft is expected to cost about 150 million euros (about $194 million), while the DART spacecraft is slated to cost about $150 million, mission officials said.
Follow Miriam Kramer?@mirikramer?and?Google+. Follow us?@Spacedotcom,?Facebook?and?Google+. Original article on?Space.com
Copyright 2013 Space.com, a TechMediaNetwork company. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
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Chamber President: State needs Panthers to stay in Charlotte
CHARLOTTE, NC (WBTV)- The Charlotte Chamber announced Friday that they are launching a public campaign to help keep the Carolina Panthers in Charlotte.
Chamber President Bob Morgan responded to questions from members of the NC General Assembly this week.
"How many times does a public official have the chance to secure a payroll of $2.8 billion for their state's economy? That's the question now facing members of North Carolina's General Assembly as they consider whether or not and how to participate in the effort to renovate Bank of America Stadium," Morgan said in his remarks.
The Panthers have asked the city and state for about $200 million in public funds to renovate and add upgrades to Bank of America Stadium.
The city of Charlotte has requested that the state legislature approve a one percent increase to the city's prepared food and beverage tax to help pay for the upgrades. That legislation has hardly advanced through one of the two chambers.
"If the State of North Carolina stands to receive nearly $300 million in tax revenues from the Panthers over the next 15 years, that's a solid business decision. Even if it means giving us the right to tax ourselves to keep the team here, we think legislators owe it to the state and the organization to seriously consider it," Morgan said.
Support for the plan eroded when a leaked financial report revealed that despite two losing seasons the Panthers have still taken in million of dollars in profits.
A statewide poll showed that nearly 88 percent of people polled said the Panthers should pay for the renovations with their own money.
"In Buffalo, a major renovation deal was just struck that includes the team putting up $35 million, the county $41 million and the state $54 million, all in return for a tether of only 10 years," Morgan said. "Buffalo and Atlanta have fought for their franchises. North Carolina needs to consider a deal and fight for its franchise as well."
Charlotte City Councilman James Mitchell, Panthers President Danny Morrison, Deputy City Manager Ron Kimble and City Attorney Bob Hageman were on a conference call with members of the Mecklenburg County legislative delegation Friday making a last ditch effort to try and get money approved for the Panthers' upgrades.
Legislative members said the money was just not there in the current political climate.
The rest of the call was spent trying to see if any grants could be won from the NC Department of Commerce to make up the rest of the requested money.
The Panthers are trying to secure the funding to begin the upgrades in January of 2014.
Copyright 2013 WBTV. All rights reserved.
Source: http://southcharlotte.wbtv.com/news/news/83792-chamber-president-state-needs-panthers-stay-charlotte
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Kerry urges Iraq to stop arms flow to Syria on Baghdad visit
Jason Reed / Reuters
U.S. Secretary of State John Kerry meets with Iraq's Prime Minister Nouri al-Maliki in Baghdad, Iraq, March 24, 2013.
By Arshad Mohammed, Reuters
Secretary of State John Kerry made an unannounced visit to Iraq on Sunday and said he told Prime Minister Nuri al-Maliki of his concern about Iranian flights over Iraq carrying arms to Syria.
Washington believes such flights and overland transfers take place nearly every day and help Syrian President Bashar al-Assad in his efforts to crush a two-year-old revolt against his rule, said a U.S. official, who spoke on condition of anonymity.
Kerry said he had told Maliki the Iranian flights through Iraqi airspace were "problematic".
"Anything that supports President Assad is problematic," Kerry told reporters. "I made it very clear to the prime minister that the overflights from Iran ... are in fact helping to sustain President Assad and his regime."
Speaking before the meeting, the U.S. official said the Iraqi government had inspected only two flights since last July and that Kerry would argue Iraq did not deserve a role in talks about neighboring Syria's future unless it tried to stop the suspected arms flow.
Iraqi officials denied allowing the transfer of weapons from Iran to Syria through Iraqi airspace. Abbas al-Bayati, a member of the Security and Defence parliamentary committee, said: "We have done our duty by randomly inspecting a number of Iranian flights and we did not find any leaked or smuggled weapons."
"If the U.S. is keen to push us to do more they have to give us the information that they have relating to this," he said.
More than a decade after the U.S.-led invasion that toppled Saddam Hussein, Iraq still struggles with insurgents, sectarian friction and political feuds among Shi'ite, Sunni and Kurdish factions who share power in the government of Shi'ite premier Maliki.
Sunni Islamist insurgents linked to al Qaeda and invigorated by the war next door in Syria - where Sunni rebels are battling Assad, an ally of Shi'ite Iran - are regaining ground in Iraq and have stepped up attacks on Shi'ite targets in recent months in an attempt to provoke a wider sectarian confrontation.
Kerry held talks with representatives of all three communities, including Osama al-Nujaifi, the Sunni speaker of parliament.
He also spoke by telephone to Massoud Barzani, president of Iraq's Kurdish region, whose regional government is pressing ahead with plans to build an oil pipeline to Turkey that Washington fears could lead to the break-up of Iraq.
According to reporters at a picture-taking session at the start of Kerry's talks with Maliki, the U.S. diplomat appeared to joke that Hillary Clinton, his predecessor, had said Iraq would do whatever Washington asked.
"The Secretary told me that you're going to do everything that I say," Kerry said, according to the reporters.
"We won't do it," Maliki, also joking, replied, the reporters said.
SUICIDE BLASTS
In his talks with Maliki, Kerry also asked the Iraqi prime minister and his cabinet to reconsider a decision to postpone local elections in two Sunni-majority provinces, Anbar and Nineveh, the U.S. official said.
The Iraqi cabinet last week postponed the votes, which were due on April 20, for up to six months because of threats to electoral workers and violence there - a step Washington believes will only increase tensions.
While violence has fallen from the height of the sectarian slaughter that killed tens of thousands in 2006-2007, insurgents have carried out at least one major attack a month since U.S. forces left. Bombings and killings still happen daily, often aimed at Shi'ite areas and local security forces.
More than a dozen car bombs and suicide blasts tore through Shi'ite Muslim districts in the Iraqi capital Baghdad and other areas on Tuesday, killing nearly 60 people on the 10th anniversary of the U.S.-led invasion that ousted Saddam.
Further complicating security, thousands of Sunni protesters have rallied in Anbar against Maliki, whose Shi'ite-led government they accuse of marginalizing their minority sect since the fall of Sunni strongman Saddam.
Additional reporting by Suadad al-Salhy
Copyright 2013 Thomson Reuters. Click for restrictions.hall of fame occupy dc ufc 143 fight card my fair lady conversion disorder the chronicle spinal stenosis
Sunday, March 24, 2013
PFT: Rex Ryan doesn't know his starting QB yet
Getty ImagesThe bad news for Browns running back Trent Richardson this week is that he can no longer use the top of his helmet to ram opponents.? The worse news is that he now faces civil charges of assaulting a pair of women last December.
The only good news is that he?s not accused of ramming them with the top of his helmet.
According to the Cleveland Plain Dealer, Krystal Jones and Kathleen Hunter filed a lawsuit on Friday, claiming that Richardson, his girlfriend, and his brother, Terrell, verbally and physically assaulted the duo at Richardson?s home.
The incident occurred after the Browns? December 9 win over the Chiefs.? A celebration at Richardson?s house lasted into the morning hours of Monday, December 10, with Richardson?s girlfriend, Sevina Fatu, inviting Jones and Hunter to attend.
The women claim that Richardson at one point asked them to leave and that, while in the driveway, Richardson ?verbally accosted? them, ?shout[ing] and curs[ing]? that the women has ??disrespected his house?? by slamming a door.? Richardson then allegedly slammed a fist onto the hood of Jones? car, causing damage in excess of $1,500.
The women claim that, as they tried to leave, Richardson stood behind the car and called for Fatu to come out and ?attack? them.? Fatu then ?opened the driver?s door and began pummeling? Kathleen Hunter ?with her fists.?? Two other unnamed women joined the fray, beating Hunter at the alleged urging of Richardson.
Next, the trio allegedly ?proceeded to beat and pummel Plaintiff Krystal Jones with their fists and feet,? at the direction of Trent Richardson.
Jones and Hunter claim that, after they were able to drive away, they stopped the car, called police, and sought medical attention.
The Browns told the Plain Dealer that they are ?aware of the situation, but will not comment at this time.?
It?s unclear whether the situation was investigated by the authorities for criminal prosecution, and if so whether a decision was made to prosecute, or not.
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Syria rebels seize southern base, border area
By Erika Solomon
BEIRUT (Reuters) - Rebels seized an air defense base near Syria's strategic southern international highway on Saturday, activists said, a gain that could bolster opposition fighters trying to secure supply routes to the capital Damascus.
Syria's southern provinces bordering Jordan and Israel have become an increasingly significant battleground as the capital comes into play, with President Bashar al-Assad's forces and his loyalist militias hitting back hard to prevent rebel advances.
The Britain-based Syrian Observatory for Human Rights, which has a network of sources across Syria, said the base commander was among those killed in the two-week battle for the air defense site in Deraa province bordering Jordan.
"Fighters from the Nusra Front, Yarmouk Martyrs Brigade, and other battalions seized control of the 38th division air defense base, near the town of Saida on the Damascus-Amman highway, after 16 days of fierce clashes," the Observatory said.
The Nusra Front is an Islamist militant group suspected of links to al Qaeda and blacklisted by the United States as a "terrorist group". Its forces, which include foreign fighters, have come to increasing prominence in the revolt.
Videos published by opposition activists showed cheering fighters driving tanks around the base and loading boxes of ammunition onto flatbed trucks. The rebels also said in the videos they had freed dozens of prisoners held at the base.
A video uploaded by the Observatory showed what it said was the body of base commander General Mahmoud Darwish lying in a pool of blood in a bathroom.
Other activist videos showed the corpses of soldiers in camouflage fatigues scattered in the grass outside the base, shot in the head.
It was not immediately possible to verify the pictures or opposition reports. The Syrian government has severely restricted access to Syria for foreign journalists and international aid groups.
CLASHES NEAR ISRAEL BORDER
Fighting has also raged near the border with Israel, which is increasingly concerned Islamist rebels may be emboldened to end the quiet on the Golan front maintained by Assad and his father before him during their four decade rule of Syria.
Israel captured the Golan plateau from Syria in the 1967 Middle East war.
Rebels on Wednesday overran at least three towns near the Israeli-Syrian disengagement line but appeared to lose ground after militias loyal to Assad pushed them back in a fierce battle.
Rami Abdelrahman, head of the Observatory, said he recorded one of the heaviest single death tolls for rebels in the fighting near the Israeli border.
"We have 35 fighters recorded by name and at least 20 more missing, this is a huge number to be lost in a single battle and shows how hard they (Assad's forces) are fighting for these areas," Abdelrahman told Reuters.
He said the pro-government militias involved were made up of fighters from Syria's Druze minority, a sect which for some time had stayed on the sidelines of the conflict but now increasingly appears to be throwing its weight behind Assad.
Their involvement could increase sectarian bloodshed in Syria, already wracked by tensions between the Sunni Muslim majority that has led the uprising and the Alawite minority to which Assad belongs.
Tit-for-tat kidnappings and killings between the sects have become common as the uprising spiraled into a bloody civil war that has killed more than 70,000 people.
Alawite opposition campaigners, increasingly concerned for the fate of their community as fighting continues, will meet this weekend to discuss options for supporting a democratic alternative to Assad's rule and try to distance themselves from security forces attempts to crush the revolt.
(Editing by Sophie Hares)
Source: http://news.yahoo.com/syria-rebels-seize-embattled-southern-province-111154873.html
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Winter storm dumps snow on Great Plains, Midwest
More than a foot of snow fell in some places across the Great Plains and Midwest Saturday in an early spring snowstorm.?The snow started falling around midnight in northeast Colorado with the snowstorm moving into northwest Kansas and southwest Nebraska.
JC Hobbs directs his wife Sarah as they help to pull a van and U-Haul up a hill outside Calhan, Colo. as a snowstorm continued to bring bad weather to the Colorado Springs area Saturday. Ten to 15 inches of snow had fallen by Saturday afternoon north of Interstate 70 in northwest Kansas and northeast Colorado.
Michael Ciaglo/The Colorado Springs Gazette/AP
Enlarge?An early spring snowstorm forced the cancellation of more than 100 flights at Denver International Airport and closed several roads Saturday as it moved eastward, dumping more than a foot of snow in some places.
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The snow started falling around midnight in northeast Colorado and then moved into northwest Kansas and southwest Nebraska.
Ten to 15 inches of snow had fallen by Saturday afternoon north of Interstate 70 in northwest Kansas and northeast Colorado, with another 1 to 2 inches expected in the area, said Ryan Husted, a meteorologist with the National Weather Service in Goodland, Kan., where 15 inches of snow had fallen.
The storm also dropped up to 7 inches of snow in southwestern Nebraska before tapering off Saturday afternoon, said David Pearson, a meteorologist with the National Weather Service near Omaha, Neb.
"But the wind is really blowing, so visibility in those areas is still going to be pretty low," Pearson said.
Husted said winds gusting at speeds of up to 45 mph were creating snow drifts of 2 to 3 feet in parts of Kansas, Colorado and Nebraska.
I-70 had been shut down Saturday from Denver to Colby, Kan., because of poor visibility. The northbound lanes of Interstate 25 also were closed south of Fort Collins, Colo., because of multiple accidents.
"It's a mess here," said Jerry Killingsworth, a National Weather Service meteorologist also based in Goodland, Kan. "Heavy, wet snow, tree limbs down."
At the Goodland 24/7 truck stop, truckers milled around. With roads in the area closed, they are "just waiting," said Samantha Lamb, the truck stop's assistant manager.
"Our hotel across the street from us is pretty full," Lamb said. "Our parking lot has a good 35, 40 trucks in it."
As the system moved eastward, it threatened to inconvenience fans attending the NCAA men's college basketball tournament in Kansas City.
Scott Blair, a meteorologist in Pleasant Hill, Mo., said light showers and drizzle began switching over to snow Saturday afternoon in Kansas City and western Missouri. The heaviest snowfall was expected overnight, with up to 6 inches forecast for the Kansas City metropolitan area.
"If people don't need to be out driving tomorrow that would certainly be recommended," he said.
Dan Gavitt, vice president of the NCAA men's basketball championships, said teams and officials already are onsite and that no game delays are anticipated.
"This region routinely has winter snow and has the appropriate equipment and procedures to manage these winter conditions," Gavitt said in a written statement. "We encourage fans planning to attend games to pay attention to the weather, use good judgment and follow any directions from local authorities regarding travel and weather."
North Carolina coach Roy Williams was nonplussed.
"It's no distraction, unless the roof goes off, we'll still be able to play and the whole bit like that," Williams said.
Elsewhere, some churches and other organizations were calling off events. Among them, the final game of the Emporia State baseball series with Southwest Baptist was canceled.
Denver International Airport spokesman Heath Montgomery said about 106 flights have been canceled, many of which involved commuter jets headed to nearby destinations or to mountain towns.
The Colorado Avalanche Information Center said up to a foot of new snow in the mountains could create dangerous avalanche conditions.
Colorado State Patrol troopers also spent part of Saturday working a crash near Johnstown involving a tractor-trailer that burst into flames. An estimated 20 to 50 vehicles, including four tractor-trailers, crashed or slid off the roadway in the area. The patrol said several people were hospitalized, but no fatalities have been reported.
The system will move into Illinois and Indiana overnight and into Sunday.
Meteorologist Dan Smith with the National Weather Service in Lincoln, Ill., said snowstorms aren't uncommon in early spring. The latest the area has seen snow, he said, was April 23, in 1910.
"One good thing about (the snowstorms) is it doesn't matter how much you get, it usually doesn't stick around too long because temperatures start to warm up pretty good," he said.
Farther south, tornadoes were possible in Louisiana and Mississippi, while strong winds and low humidity could lead to forest fires and wildfires in parts of New Mexico and West Texas.
___
Associated Press writers Jason Keyser in Chicago, Thomas Peipert in Denver, David Skretta in Kansas City, Mo., and Margery A. Beck in Omaha, Neb., contributed to this report.
Source: http://rss.csmonitor.com/~r/feeds/csm/~3/njsNYNVaBvQ/Winter-storm-dumps-snow-on-Great-Plains-Midwest
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